Our unique

Technology

At Hyaline, we integrate state-of-the-art science into every formulation. Our fillers are based on a unique PEG-based cross-linking method and a proprietary IPN-S (Sequential Interpenetrating Polymer Network) technology.

What is IPN-S?

IPN-S stands for a Sequential Interpenetrating Polymer Network – a system where two polymer chains interweave without chemical mixing. This technique improves:

Thermolability

Improved thermal stability: the product remains stable and effective even under varying temperature conditions.

Elasticity

Greater elasticity: the material adapts more naturally to skin tissues, enhancing the aesthetic outcome.

Resistance to degradation

Increased resistance to degradation: the filler lasts longer in the body, maintaining its effect over an extended period.

What is IPN-S?

IPN-S stands for a Sequential Interpenetrating Polymer Network – a system where two polymer chains interweave without chemical mixing. This technique improves:

Thermolability

Improved thermal stability: the product remains stable and effective even under varying temperature conditions.

Elasticity

Greater elasticity: the material adapts more naturally to skin tissues, enhancing the aesthetic outcome.

Resistance to degradation

Increased resistance to degradation: the filler lasts longer in the body, maintaining its effect over an extended period.

Biomimetic Innovation

Inspired by nature, our technology mimics biological processes by combining Hyaluronic Acid (HA) with Calcium Hydroxyapatite (CaHA). This synergistic combination supports skin regeneration, collagen production, and a natural anti-aging cycle.

Why PEG Matters

PEG is FDA-approved and widely used in medical applications
30x safer than BDDE (from a biological perspective)
Improves mechanical performance and elasticity
Minimizes toxicity and risk of adverse reactions

Product Safety & Quality

Our raw materials meet the highest purity standards:

HA with less than 0.1% protein/DNA residuals
Endotoxins below 0.05 IU/mg
High biocompatibility and minimal inflammation risk
Virtually zero granuloma formation